Effects of individualized positive end-expiratory pressure on intraoperative oxygenation in thoracic surgical patients: study protocol for a prospective randomized controlled trial

Abstract Background Intraoperative hypoxemia and postoperative pulmonary complications (PPCs) often occur in patients with one-lung ventilation (OLV), due to both pulmonary shunt and atelectasis.It has been demonstrated that individualized positive end-expiratory pressure (iPEEP) can effectively improve intraoperative oxygenation, increase lung com

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Characterization of single cell derived cultures of periosteal progenitor cells to ensure the cell quality for clinical application.

For clinical applications of cells and tissue engineering products it is of importance to characterize the quality of the used cells in detail.Progenitor cells from the periosteum are already routinely applied in the clinics for the regeneration of the maxillary bone.Periosteal cells have, in addition to their potential to differentiate into bone,

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Adherence to minimal retesting interval for HbA1c, vitamin D and thyrotropin in the University Hospital of Nepal

Background: Laboratory testing plays a critical role in healthcare decision-making; however, concerns regarding overutilization and inappropriate testing persist.Minimum retesting intervals serve as a tool to optimize testing practices and resource allocation.This study aimed to assess adherence to minimum retesting interval guidelines and estimate

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